Neurophysiological data acquisition using multi-electrode arrays and/or (semi-) chronic recordings frequently has to deal with low signal-to-noise ratio (SNR) of neuronal responses and potential failure of detecting evoked responses within random background fluctuations.Conventional methods to extract action potentials (spikes) from background nois

For grant proposals the investigator has to include an estimation of sample size.The size of the sample should be adequate enough so that there is sufficient data to reliably answer the research question being addressed by the study.At the very planning stage Cartoon Art of the study the investigator has to involve the statistician.To have meaningf

Abstract Background Impaired insulin sensitivity is a key abnormality underlying the development of type 2 diabetes.Measuring insulin sensitivity is therefore of importance in identifying individuals at risk of developing diabetes and for the evaluation of Data Cable diabetes-focused interventions.A number of measures have been proposed for this pu